A brief history of The Christie

The Christie was named in honour of Richard and Mary Christie who were instrumental in setting up the cancer centre. You can read more about Richard and Mary Christie further down this page.

Confronted with new diseases such as mule spinners' cancer and chimney sweep's cancer, doctors started looking for possible links to machine oils and airborne soot. At this time there were 30 beds and 463 patients each year.

Early treatments including extracts of cow stomach juice with some staff were fearful about contracting cancer.

But early work became the forerunner of many cancer treatment breakthroughs made by researchers at The Christie. Milestones throughout the 20th century included:

  • 1901 - use of X-rays for therapy
  • 1905 - use of radium for therapy
  • 1932 - development of the "Manchester Method" of radium treatment
  • 1944 - world's first clinical trial of Stilboestrol a breast cancer drug
  • 1970 - world's first clinical use of Tamoxifen a breast cancer drug
  • 1986 - world's first use of cultured bone marrow for leukaemia treatment
  • 1991 - world's first single harvest blood stem-cell transplant
  • 1996 - inventing photo-dynamic therapy for skin cancer
  • ….and 'world firsts' are still continuing in the 21st century.

Surgery was suspended in 1915 because of first world war work, and during the second world war Christie staff had to keep the radium safe from potential bombing whilst they carried on treating patients.

From 1931 The Christie was linked with the Holt Radium Institute which gave radium treatments for patients in local hospitals. The two institutions then moved from Stanley Grover to a new building in Withington, south Manchester, where The Christie's main site remains to this day

In the 1930s and onwards, Dr Ralston Paterson built a team of physicists and clinicians who turned the hospital into a world recognised centre for the treatment of cancer by radiation. The Christie set the first international standards for radiation treatment in 1932.

Dr Paterson's wife, Dr Edith Paterson, started research work at the Christie in 1938 - initially alone, unpaid and having to provide her own equipment. She too became a world-renowned pioneer in biological dosimetry, childhood cancers and anti-cancer drug treatment methods. You can read more about Ralston and Edith Paterson further down this page.

In 1948 The Christie became part of the newly created NHS.

Dr Eric Easson was appointed Director of The Christie following Dr. Paterson's retirement in 1962, and remained as Director until his retirement in 1979.

His initial interest was in leukaemia and he became internationally known for his work on curability. Early detection of cancer was his abiding concern and for eight years he was chairman of the Commission on Cancer Control of the International Union against Cancer (the UICC). He was also the President of the Royal College of Radiologists from 1975 until 1977, and was awarded the CBE in 1978.

Many subsequent clinical and scientific staff members have made significant contributions to research, education and clinical developments - lending their expertise to the broader UK and world community.

Some important people in The Christie's history

A bust statue of Richard Christie.
The bronze bust statue of Richard Christie in The Christie boardroom

Richard Copley Christie was born on 22 July 1830 at Lenton in Nottinghamshire. In 1853, he graduated from Oxford in law and history and went on to become a barrister and a professor at Owens College in Manchester (now part of the University of Manchester).

In 1861, Richard married Mary Ellen (also known as Helen). Both Richard and Mary were committed philanthropists and supported charitable causes throughout their lives.

After Sir Joseph Whitworth died in 1887, Richard was appointed as one of the 3 legatees of his will. He was left £300,000 in the will, with the instruction to use this for charitable and educational purposes.

The 3 legatees of the will donated some of the money to Owens College, but Richard Christie urged the other legatees to support the founding and supporting of a new cancer hospital. This was a special interest of his wife, Mary Christie. Later, Richard would admit that he wasn’t sure about the idea for the cancer hospital, and it was his wife who had convinced him how important it was.

Christie promised financial support of £1,000 and with other donations from other backers, he was able to raise £10,000 to build the new cancer hospital.

The committee that Richard formed identified a part of the land that Owens College had just purchased in 1888 with the Whitworth money, known as the Stanley Grove estate as a possible site for the cancer hospital. The estate included 11 houses with 12 and a half acres of ground and is where the present Manchester Royal Infirmary now stands.

On 7 November 1892, the Cancer Pavilion and Home was opened under the presidency of Richard Christie. On the following day, Professor Sheridan Delepine proposed that a ward be named after Mrs Helen Christie in recognition of her contributions. 2 months later, Mrs Christie donated a bed and named it after her sister, Jane Rogers, who had also contributed about £1,000 towards the founding of the hospital.

In October 1899, the freedom of the city of Manchester was conferred upon Richard Christie. He died at Ribsden in January 1901, with his wife surviving him. Richard left his collection of books to the Owens College, as well as money to maintain its Christie Library. He also left legacies to the Royal Holloway College, to the Library Association of the United Kingdom, and to various medical and other charities.

Following the death of Richard Christie, the Board of Management of the Cancer Pavilion and Home recommended a change of name to ‘The Christie Hospital’. This was a ‘lasting memorial of the great services rendered to the Charity by the late Mr Christie and Mrs Christie.’

In 1902, 2 bronze busts of Mr and Mrs Christie, sculpted by Mr John Cassidy, were given to the Board by Treasurer, Mr SL Helm to display in the entrance hall. These are still in The Christie boardroom today.

A bust statue of Mary Christie.
The bronze bust statue of Mary Christie in The Christie boardroom

A portrait of Richard Christie by Mr. T. B. Kennington is in the Christie Library at the University of Manchester, where it was placed by his friends shortly before his death.

Ralston Paterson was born on 21 May 1897 in Edinburgh. After leaving the army in 1919, he worked as a consultant radiologist in South Africa, and taught radiology at the University of Chicago.

During his time in the United States, Ralston married Edith Jones. When Ralston was made Director of the Holt Radium Institute in 1931, he and Edith moved to Manchester and stayed there until his retirement.

Ralston Paterson played a pivotal role in establishing Manchester as the leading centre of radium therapy in Britain and in promoting the professionalisation of radiotherapy. He developed the Manchester system of radium dosimetry, and a regulatory framework for standardised treatment for a population of more than 4 million. Later he sought to educate the public to overcome their fears of cancer, and introduced social and psychological services for patients.

In addition to improving the treatment of cancer, Paterson also engineered better safety measures for staff and patients, and increased support of clinical and laboratory research.

In early 1932, Paterson spent 3 weeks in Brussels and returned with a new method of making moulds for the application of radium. The mould room at The Christie was soon built for this purpose.

In 1933, Edith Paterson began unpaid work at the hospital researching tissue culture. 10 years after she began this work, she was formally appointed to the hospital staff as a research radiobiologist. Edith later became an internationally-recognised researcher in the fields of biological radiation dosimetry, childhood cancers and cancer drug treatment methods.

Ralston Paterson retired from The Christie in 1962 and he Edith spent the rest of their lives running a cattle and sheep farm in Stenreishill in Scotland. Ralston died in August 1981, and his wife lived until September 1995.

The former Paterson building and the current Paterson cancer research centre at The Christie were named for the Patersons’ contributions to cancer research. A drawing of Ralston Paterson now hangs in The Christie boardroom.

A photo of a drawing of Ralston Paterson.
The drawing of Ralston Paterson in The Christie boardroom

For over 100 years The Christie has played a crucial role in the advancement of cancer treatment and care.

We are one of Europe's leading cancer centres but have always retained our treasured 'family spirit', with the patient being at the very heart of everything we do.

Our world firsts and proud moments have continued into the 21st century…

  • 2002 - World's first clinical use of image guided radiotherapy on a radiotherapy machine
  • 2008 - Survival rates following surgery for bladder cancer recognized as better than anywhere else in UK
  • 2008 - First UK hospital to be accepted as a member of Organisation of European Cancer Institutes. First UK organization to be officially accredited as a Comprehensive Cancer Centre, becoming just one of only eight centres to have this status in Europe
  • 2009 - First trials in Europe undertaken for pioneering radioimmunotherapy cancer treatment
  • 2010 - In September a Christie School of Oncology, the first of its kind in the UK, was launched
  • 2010 - Signed a £14million private patient joint venture with HCA International in 2010 to develop The Christie Clinic - a new private patient cancer unit to increase income for our NHS services
  • 2010 - Opened a £17million radiotherapy centre in Oldham
  • 2010 - The Christie's patient treatment centre housing the world's largest single site early phase clinical trials unit and largest chemotherapy facility in the UK opens
  • 2011 - Opened a £17million radiotherapy centre in Salford
  • 2011 - Two new surgical theatres opened
  • 2012 - Launched The Christie's 20:20 Vision to transform cancer treatments and improve outcomes for patients, following year-long engagement phase with many of our stakeholders
  • 2013 - Opened a £3.8million brachytherapy and molecular radiotherapy unit, housing the UK's largest brachytherapy service
  • 2013 - Launched a mobile chemotherapy unit to bring Christie care closer to home for patients in Bolton, Failsworth, Hyde, Rochdale and Trafford

Last updated: March 2025