Name

Shaishav Dhage

Job title

Consultant Endocrinologist

Email Address

The-Christie.Endocrinology@nhs.net

Qualifications

MBBS, DNB Medicine, MRCP, MD, PG Cert Med Ed.

Specialities

Endocrinology, Diabetes, Internal medicine

Started at The Christie (Year)

2019

Responsibilities

Consultant in Endocrinology, Diabetes and General Internal Medicine

Professional biography

Dr Shaishav S. Dhage, qualified from Pune University, Maharashtra, India and continued his higher training, completing post-graduation in general internal medicine with Diplomate of National Board of Examinations, New Delhi, India.

He completed Royal College Sponsored Fellowship in Endocrinology and Diabetes at University Hospital South Manchester, UK in 2013. He has rotated through various hospitals in the Northwest region of England, completing his training as Specialist Registrar in Endocrinology, Diabetes and General Internal Medicine.

Dr Dhage has completed his research degree at University of Manchester under supervision of Prof. Handrean Soran and Prof. Rayaz A Malik. During this period, he contributed to various multinational, multi-centre, industry sponsored cardiovascular risk prevention drug trials. He has published abstracts and done poster presentations at various national and international conferences.

He successfully defended the thesis titled “The Utility of Corneal Confocal Microscopy in the Detection and Follow-up of Small Fibre Neuropathy in Diabetes and Sexual Dysfunction”, to achieve his MD in Medicine.

Since 2019, Dr Dhage has been a consultant oncoendocrinologist and acute oncologist at The Christie in Manchester, the largest single site cancer centre in Europe. He leads the services of thyroid eye disease and congenital adrenal hyperplasia at the endocrine unit at The Christie, the 3rd largest tertiary endocrine unit in the UK. He also has special interest in reproductive endocrinology, andrology, immunotherapy related endocrinopathies and adrenal disorders. He is involved as a principal and sub-investigator for various clinical trials in endocrinology at The Christie.

Dr Dhage also serves on the steering committees of – clinical affairs core committee (CACC) and Clinical Endocrinology Update (CEU) Committee for American Society of Endocrinology. He delivers webinars on a regular basis for the monthly webinar series for American Society of Endocrinology.

Medical education is his passion, and he regularly delivers various teaching sessions and presentations for undergraduate students and postgraduate trainees on a regular basis. He currently works as a clinical lead for Year 3 and Year 5 MBChB students at University of Manchester. In addition, he also extends clinical and educational supervision to the postgraduate trainee doctors at various stages of their training. He is involved in teaching for MRCP SCE endocrinology courses conducted locally in Manchester. He is also a GMC approved appraiser for postgraduate doctors and consultant colleagues.

Research Interest

Reproductive endocrinology, hypogonadism, pituitary and adrenal disorders, thyroid eye disease, diabetic peripheral neuropathy

Educational Interests

Clinical and bed side teaching, problem based learning, undergraduate and postgraduate medical education

Publications

1. Small fibre pathology is associated with erectile dysfunction in men with type 2 diabetes. Dhage S, Ho JH, Ferdousi M, Kalteniece A, Azmi S, Adam S, Marshall A, Jeziorska M, Donn R, Soran H, Malik RA.Diabetes Metab Res Rev. 2020 Mar;36(3):e3263. doi: 10.1002/dmrr.3263. Epub 2019 Dec 18.PMID: 31833632
2. Efficacy and safety of PCSK9 monoclonal antibodies. Iqbal Z, Dhage S, Mohamad JB, Abdel-Razik A, Donn R, Malik R, Ho JH, Liu Y, Adam S, Isa B, Stefanutti C, Soran H. Expert Opin Drug Saf. 2019 Dec;18(12):1191-1201. doi: 0.1080/14740338.2019.1681395. Epub 2019 Nov 20. PMID: 31623472 Review.
3. Male sexual dysfunction in obesity: The role of sex hormones and small fibre neuropathy.Ho JH, Adam S, Azmi S, Ferdousi M, Liu Y, Kalteniece A, Dhage SS, Keevil BG, Syed AA, Ammori BJ, Ahern T, Donn R, Malik RA, Soran H. PLoS One. 2019 Sep 11;14(9):e0221992. doi: 10.1371/journal.pone.0221992. eCollection 2019.PMID: 31509565 Free PMC article.
4. Effect of Roux-en-Y Bariatric Surgery on Lipoproteins, Insulin Resistance, and Systemic and Vascular Inflammation in Obesity and Diabetes.Yadav R, Hama S, Liu Y, Siahmansur T, Schofield J, Syed AA, France M, Pemberton P, Adam S, Ho JH, Aghamohammadzadeh R, Dhage S, Donn R, Malik RA, New JP, Jeziorska M, Durrington P, Ammori BA, Soran H. Front Immunol. 2017 Nov 15;8:1512. doi: 10.3389/fimmu.2017.01512. eCollection 2017.PMID: 29187850 Free PMC article.
5. Bariatric surgery as a model to explore the basis and consequences of the Reaven hypothesis: Small, dense low-density lipoprotein and interleukin-6. Adam S, Liu Y, Siahmansur T, Ho JH, Dhage SS, Yadav R, New JP, Donn R, Ammori BJ, Syed AA, Malik RA, Soran H, Durrington PN. Diab Vasc Dis Res. 2019 Mar;16(2):144-152. doi: 10.1177/1479164119826479.PMID: 31014098 Clinical Trial.
6. Hypercholesterolaemia - practical information for non-specialists. Soran H, Adam S, Mohammad JB, Ho JH, Schofield JD, Kwok S, Siahmansur T, Liu Y, Syed AA, Dhage SS, Stefanutti C, Donn R, Malik RA, Banach M, Durrington PN. Arch Med Sci. 2018 Jan;14(1):1-21. doi: 10.5114/aoms.2018.72238. Epub 2017 Dec 19. PMID: 29379528 Free PMC article.
7. Risk Factors for Failure of Direct Current Cardioversion in Patients with Type 2 Diabetes Mellitus and Atrial Fibrillation. Soran H, Banerjee M, Mohamad JB, Adam S, Ho JH, Ismaeel SM, Dhage S, Syed AA, Abdulla IMA, Younis N, Malik RA.Biomed Res Int. 2018 Mar 12;2018:5936180. doi: 10.1155/2018/5936180. eCollection 2018.PMID: 29721508 Free PMC article. Clinical Trial.
8. Diabetic Neuropathy Is Characterized by Progressive Corneal Nerve Fiber Loss in the Central and Inferior Whorl Regions. Ferdousi M, Kalteniece A, Petropoulos I, Azmi S, Dhage S, Marshall A, Boulton AJM, Efron N, Faber CG, Lauria G, Soran H, Malik RA.Invest Ophthalmol Vis Sci. 2020 Mar 9;61(3):48. doi: 10.1167/iovs.61.3.48.PMID: 32232351