The Christie Charity
Jonathan Lim
Name
Jonathan Lim
Job title
Clinical Senior Lecturer and Consultant Medical Oncologist in Advanced Immunotherapy and Cell Therapy
Email Address
of secretary/PA kathryn.mccreavey@nhs.net
Phone number
of secretary/PA 0161 918 7894 (Kath McCreavey)
Qualifications
BHSc, MBBS, MRes(Dist), PhD, MRCP(UK), MRCP(Medical Oncology), AFHEA
Specialities
Medical oncology, Immunotherapy, Cellular therapies
Started at The Christie (Year)
2015 (2024 as consultant)
Responsibilities
Dr Jonathan Lim is a consultant medical oncologist within the advanced immunotherapy and cell therapy (AICT) team. His clinical practice is in caring for adult patients with solid cancer receiving novel immunotherapies and advanced cell therapies within an active clinical trials research portfolio in AICT.
Professional biography
Dr Jonathan Lim is a clinical senior lecturer and honorary consultant medical oncologist in advanced immunotherapy and cell therapy for solid cancers at The University of Manchester and The Christie NHS Foundation Trust. He is passionate about translational research and in developing novel advanced therapies, especially in the settings of early-phase clinical trials and first-in-human studies.
Dr Lim completed his medical degree at St George’s University of London in 2011, and commenced his career as an Academic Foundation Trainee in Brighton. In 2013, he was appointed NIHR Academic Clinical Fellow in Clinical Pharmacology and Therapeutics, and moved to Manchester where he worked on circulating tumour cells and technology platforms for precision medicine in melanoma, for which he was awarded Distinction for his MRes degree at The University of Manchester.
In 2022, Dr Lim successfully defended his PhD investigating the role of dendritic cells in cancer, under the aegis of the prestigious Wellcome-Imperial 4i Clinical Fellowship at The Francis Crick Institute and Imperial College London. His PhD research has been recognised with the national ACP McElwain Prize for Translational Research and the international AACR-Pezcoller Foundation Scholar-in-Training Award.
To further develop as a clinician-scientist in the field of cancer immunotherapy, Dr Lim obtained the Crick Postdoctoral Clinical Fellowship to work on translational research models to test novel immunotherapies at The Francis Crick Institute, and an Honorary Clinical Research Fellowship at The Royal Marsden. He also obtained the ICF-ESMO Clinical Unit Visiting Fellowship to enhance his expertise in cell therapy with Prof John Haanen at the Netherlands Cancer Institute in Amsterdam. In Manchester, Dr Lim is currently a project co-lead of the MANIFEST consortium, a UK-wide multi-million research programme investigating biomarkers for response to cancer immunotherapy.
He actively serves as a member of the ESMO Translational Research Faculty, the ESMO Resilience Task Force, and is an Associate Editor of the ESMO IOTECH journal. He is an alumnus of the ESMO Leaders Generation Programme.
Research Interest
Cancer immunology; Cancer immunotherapy; Cell therapy (TILs, TCR-T, CAR-T, etc.); Cancer vaccines; Advanced therapies; Translational research; Immune biomarkers; Immunogenic cell death; Antigen presentation; Early-phase clinical trials; First-in-human studies.
Educational Interests
Dr Jonathan Lim is enthusiastic about medical education, and training and mentorship of students, doctors and allied health professionals. He is an Accredited Educator by The Royal College of Physicians and Associate Fellow of The Higher Education Academy (AFHEA). Internationally, he is a selected mentor for the ESMO Virtual Mentorship Programme and a member of the ASCO Medical Education Community of Practice Mentorship Committee.